Henrique Silva Fernandes, Maria João Ramos, and Nuno M.F.S.A. Cerqueira Published on 18th September 2018 Journal: ACS Catalysis http://dx.doi.org/10.1021/acscatal.8b02321 | Download citation Abstract Serine Hydroxymethyltransferase (SHMT) is an important drug target to fight malaria – one of the most devastating infectious diseases that accounted in 2016 with 216 million new cases and almost 450 thousand deaths. In … Continue reading The catalytic mechanism of the Serine Hydroxymethyltransferase – a computational ONIOM QM/MM study